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Genetic risk factor for Bipolar disorder
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<blockquote data-quote="Nomad" data-source="post: 762107" data-attributes="member: 4152"><p>Im rushing and wanted to get this here somewhere fast….When our adopted special needs adult child found her birth family, she discovered both her parents suffered from mental illness like herself and many in the families with Bipolar disorder.</p><p></p><p>Sorry I don’t have a link.</p><p></p><p>It was I think on yahoo today. From neuroscience news.com</p><p></p><p>Headline said :</p><p>Researchers Find First Strong Genetic risk Factor for Bipolar Disorder</p><p></p><p>This is just a little of article:</p><p></p><p>“Led by scientists at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard who collaborated with colleagues around the globe, the effort pinpoints a gene called AKAP11 as a strong risk factor for both bipolar disorder and schizophrenia.</p><p></p><p>The findings may provide clues to how lithium works, as the AKAP-11 protein is known to interact with a molecular pathway modified by the drug. While many common genetic variants of small effects have been discovered, AKAP11 is the first gene found to have a large effect on bipolar disorder risk.</p><p></p><p>This result has already kicked off new research at the Broad to further study the disorder in cells and animals, with a focus on molecular mechanisms that can in turn lead to identification of biomarkers to match patients with treatments and develop novel therapies.”</p></blockquote><p></p>
[QUOTE="Nomad, post: 762107, member: 4152"] Im rushing and wanted to get this here somewhere fast….When our adopted special needs adult child found her birth family, she discovered both her parents suffered from mental illness like herself and many in the families with Bipolar disorder. Sorry I don’t have a link. It was I think on yahoo today. From neuroscience news.com Headline said : Researchers Find First Strong Genetic risk Factor for Bipolar Disorder This is just a little of article: “Led by scientists at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard who collaborated with colleagues around the globe, the effort pinpoints a gene called AKAP11 as a strong risk factor for both bipolar disorder and schizophrenia. The findings may provide clues to how lithium works, as the AKAP-11 protein is known to interact with a molecular pathway modified by the drug. While many common genetic variants of small effects have been discovered, AKAP11 is the first gene found to have a large effect on bipolar disorder risk. This result has already kicked off new research at the Broad to further study the disorder in cells and animals, with a focus on molecular mechanisms that can in turn lead to identification of biomarkers to match patients with treatments and develop novel therapies.” [/QUOTE]
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