Malika
Well-Known Member
[FONT=verdana, arial, helvetica, sans-serif]As a footnote to my previous post, here is an abstract of one of these studies
Iron Deficiency in Children With Attention-Deficit/Hyperactivity Disorder [/FONT] [FONT=verdana, arial, helvetica, sans-serif] Eric Konofal, MD, PhD; Michel Lecendreux, MD; Isabelle Arnulf, MD, PhD; Marie-Christine Mouren, MD [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] Arch Pediatr Adolesc medication. 2004;158:1113-1115. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] ABSTRACT [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] Background Iron deficiency causes abnormal dopaminergic neurotransmission and may contribute to the physiopathology of attention-deficit/hyperactivity disorder (ADHD). [/FONT] [FONT=verdana, arial, helvetica, sans-serif]Objective To evaluate iron deficiency in children with ADHD vs iron deficiency in an age- and sex-matched control group. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Design Controlled group comparison study. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Setting Child and Adolescent Psychopathology Department in European Pediatric Hospital, Paris, France. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Patients Fifty-three children with ADHD aged 4 to 14 years (mean ± SD, 9.2 ± 2.2 years) and 27 controls (mean ± SD, 9.5 ± 2.8 years). [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Main Outcome Measures Serum ferritin levels evaluating iron stores and Conners Parent Rating Scale scores measuring severity of ADHD symptoms have been obtained. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Results The mean serum ferritin levels were lower in the children with ADHD (mean ± SD, 23 ± 13 ng/mL) than in the controls (mean ± SD, 44 ± 22 ng/mL; P < .001). Serum ferritin levels were abnormal (<30 ng/mL) in 84% of children with ADHD and 18% of controls (P < .001). In addition, low serum ferritin levels were correlated with more severe general ADHD symptoms measured with Conners Parent Rating Scale (Pearson correlation coefficient, r = 0.34; P < .02) and greater cognitive deficits (r = 0.38; P < .01). [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Conclusions These results suggest that low iron stores contribute to ADHD and that ADHD children may benefit from iron supplementation. [/FONT]
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[FONT=verdana, arial, helvetica, sans-serif][/FONT][/FONT]
[FONT=verdana,arial,helvetica,sans-serif]http://archpedi.ama-assn.org/cgi/content/full/158/12/1113#BIBL[/FONT]
[FONT=verdana, arial, helvetica, sans-serif] [/FONT]
Iron Deficiency in Children With Attention-Deficit/Hyperactivity Disorder [/FONT] [FONT=verdana, arial, helvetica, sans-serif] Eric Konofal, MD, PhD; Michel Lecendreux, MD; Isabelle Arnulf, MD, PhD; Marie-Christine Mouren, MD [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] Arch Pediatr Adolesc medication. 2004;158:1113-1115. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] ABSTRACT [/FONT]
[FONT=verdana, arial, helvetica, sans-serif] Background Iron deficiency causes abnormal dopaminergic neurotransmission and may contribute to the physiopathology of attention-deficit/hyperactivity disorder (ADHD). [/FONT] [FONT=verdana, arial, helvetica, sans-serif]Objective To evaluate iron deficiency in children with ADHD vs iron deficiency in an age- and sex-matched control group. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Design Controlled group comparison study. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Setting Child and Adolescent Psychopathology Department in European Pediatric Hospital, Paris, France. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Patients Fifty-three children with ADHD aged 4 to 14 years (mean ± SD, 9.2 ± 2.2 years) and 27 controls (mean ± SD, 9.5 ± 2.8 years). [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Main Outcome Measures Serum ferritin levels evaluating iron stores and Conners Parent Rating Scale scores measuring severity of ADHD symptoms have been obtained. [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Results The mean serum ferritin levels were lower in the children with ADHD (mean ± SD, 23 ± 13 ng/mL) than in the controls (mean ± SD, 44 ± 22 ng/mL; P < .001). Serum ferritin levels were abnormal (<30 ng/mL) in 84% of children with ADHD and 18% of controls (P < .001). In addition, low serum ferritin levels were correlated with more severe general ADHD symptoms measured with Conners Parent Rating Scale (Pearson correlation coefficient, r = 0.34; P < .02) and greater cognitive deficits (r = 0.38; P < .01). [/FONT]
[FONT=verdana, arial, helvetica, sans-serif]Conclusions These results suggest that low iron stores contribute to ADHD and that ADHD children may benefit from iron supplementation. [/FONT]
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[FONT=verdana, arial, helvetica, sans-serif][/FONT][/FONT]
[FONT=verdana,arial,helvetica,sans-serif]http://archpedi.ama-assn.org/cgi/content/full/158/12/1113#BIBL[/FONT]
