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difficult child 3 - violent rage. Strattera?
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<blockquote data-quote="flutterbee" data-source="post: 225007"><p>The number of people drugs are studied on is small. Sometimes just a couple thousand. They have specific criteria and they are tested on adults. It's not until drugs have been used off-label in the general population that they become FDA approved for children. At least that's my understanding. How many years was Prozac out before it became approved for use in children? To my knowledge it's the only AD approved by the FDA for use in children, yet we see here the vast range of AD's our kids are on or have been on in the past. And we already know that medications used for adults do not work the same with children.</p><p></p><p>Further, they test these drugs on people with the specific disorder. IOW, only on people with ADHD. The drug is not going to be studied on people with comorbid disorders, such as autism, bipolar, anxiety, etc.</p><p></p><p>In addition, too many doctors are too quick to medicate symptoms. ADHD is also over-diagnosed, in my opinion. That means more kids are going to be on Straterra when they shouldn't be and you're going to see more negative results. </p><p></p><p>I feel that too many doctors just throw medications at things and see what works. They don't take the time to fully read the studies, nor do they take the time to understand the pharmacology. I honestly believe that many of us parents - lay people - know better what our kids should be on and what they shouldn't because we have a vested interest and take the time to do the research and talk to other parents. That's one of the reasons I like my doctor so much; she knows I research and know what I'm talking about and prescribes accordingly.</p><p></p><p>Some doctors also have a medication or combination of medications that they automatically prescribe for a given diagnosis. Across the board. If that doesn't work for you, they tend to increase the dose rather than try something else. If it still doesn't work they tend to add to it rather than try something altogether different.</p><p></p><p>Some of this is from my research, some of this is first hand experience and some of this is my bias. Regardless, medication studies, approval and prescribing practices need to change.</p><p></p><p>The one example I like to use is Nexium. I think everyone has heard of the purple pill. Nexium is almost the exact same thing as Prilosec (which can now be purchased OTC). The patent for Prilosec was set to expire and the drug company came out with Nexium. They spent tons and tons of money marketing it, stating it was significantly better than Prilosec. Doctors bought into it (shame on them - they should know better) and started prescribing it like crazy. What was discovered was that there was only a 3% difference in the side effect profile between Nexium and Prilosec. But by then, millions of prescriptions had been written for an expensive brand name drug, driving up our health care costs.</p><p></p><p>Pristiq is another one. It's the new version of Effexor. Supposedly it metabolizes differently. Effexor's patent runs out in 2010, I think. The side effect of Pristiq is supposed to be better. From what I've read, I've heard both sides. However, there is only a 2 point difference on the depression scale between Pristiq and the placebo. Not enough to make me take it.</p></blockquote><p></p>
[QUOTE="flutterbee, post: 225007"] The number of people drugs are studied on is small. Sometimes just a couple thousand. They have specific criteria and they are tested on adults. It's not until drugs have been used off-label in the general population that they become FDA approved for children. At least that's my understanding. How many years was Prozac out before it became approved for use in children? To my knowledge it's the only AD approved by the FDA for use in children, yet we see here the vast range of AD's our kids are on or have been on in the past. And we already know that medications used for adults do not work the same with children. Further, they test these drugs on people with the specific disorder. IOW, only on people with ADHD. The drug is not going to be studied on people with comorbid disorders, such as autism, bipolar, anxiety, etc. In addition, too many doctors are too quick to medicate symptoms. ADHD is also over-diagnosed, in my opinion. That means more kids are going to be on Straterra when they shouldn't be and you're going to see more negative results. I feel that too many doctors just throw medications at things and see what works. They don't take the time to fully read the studies, nor do they take the time to understand the pharmacology. I honestly believe that many of us parents - lay people - know better what our kids should be on and what they shouldn't because we have a vested interest and take the time to do the research and talk to other parents. That's one of the reasons I like my doctor so much; she knows I research and know what I'm talking about and prescribes accordingly. Some doctors also have a medication or combination of medications that they automatically prescribe for a given diagnosis. Across the board. If that doesn't work for you, they tend to increase the dose rather than try something else. If it still doesn't work they tend to add to it rather than try something altogether different. Some of this is from my research, some of this is first hand experience and some of this is my bias. Regardless, medication studies, approval and prescribing practices need to change. The one example I like to use is Nexium. I think everyone has heard of the purple pill. Nexium is almost the exact same thing as Prilosec (which can now be purchased OTC). The patent for Prilosec was set to expire and the drug company came out with Nexium. They spent tons and tons of money marketing it, stating it was significantly better than Prilosec. Doctors bought into it (shame on them - they should know better) and started prescribing it like crazy. What was discovered was that there was only a 3% difference in the side effect profile between Nexium and Prilosec. But by then, millions of prescriptions had been written for an expensive brand name drug, driving up our health care costs. Pristiq is another one. It's the new version of Effexor. Supposedly it metabolizes differently. Effexor's patent runs out in 2010, I think. The side effect of Pristiq is supposed to be better. From what I've read, I've heard both sides. However, there is only a 2 point difference on the depression scale between Pristiq and the placebo. Not enough to make me take it. [/QUOTE]
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