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General Parenting
Double Edged Sword?
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<blockquote data-quote="Sara PA" data-source="post: 163869" data-attributes="member: 1498"><p>Consider too that the abrupt discontinuation of the clonodine could cause some problems. Sometimes it's not what you add but what you take away. From the Catapres prescribing information:</p><p></p><p><em>Withdrawal</em></p><p><em></em></p><p><em>Patients should be instructed not to discontinue therapy without consulting their physician. Sudden cessation of clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and tremor accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma. The likelihood of such reactions to discontinuation of clonidine therapy appears to be greater after administration of higher doses or continuation of concomitant beta-blocker treatment and special caution is therefore advised in these situations. Rare instances of hypertensive encephalopathy, cerebrovascular accidents and death have been reported after clonidine withdrawal. When discontinuing therapy with Catapres&#174; (clonidine hydrochloride, USP) tablets, the physician should reduce the dose gradually over 2 to 4 days to avoid withdrawal symptomatology.</em></p></blockquote><p></p>
[QUOTE="Sara PA, post: 163869, member: 1498"] Consider too that the abrupt discontinuation of the clonodine could cause some problems. Sometimes it's not what you add but what you take away. From the Catapres prescribing information: [I]Withdrawal Patients should be instructed not to discontinue therapy without consulting their physician. Sudden cessation of clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and tremor accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma. The likelihood of such reactions to discontinuation of clonidine therapy appears to be greater after administration of higher doses or continuation of concomitant beta-blocker treatment and special caution is therefore advised in these situations. Rare instances of hypertensive encephalopathy, cerebrovascular accidents and death have been reported after clonidine withdrawal. When discontinuing therapy with Catapres® (clonidine hydrochloride, USP) tablets, the physician should reduce the dose gradually over 2 to 4 days to avoid withdrawal symptomatology.[/I] [/QUOTE]
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Double Edged Sword?
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