My son (I am calling him R.) is 8 years old. When he was just several months old he would have crying fits during the night when he would cry without being awake for several minutes. When crying he would shake his legs. His legs would become stiff in a rhythmic fashion. Growing up his night cries stopped, but he would get similar fits when awake. The angry fits hit very unexpectedly and in reaction to very small provocations. He begins to kick, cry, accuse me, say obscenities etc. The fit begins unexpectedly, ends within half an hour and he is very reasonable after that for months, until the next fit. This problem has begun since he was only an infant, so I doubt I can fix it with psychotherapy or any kind of psychological therapy. I recently read about PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) and strangely enough a recent fit of his began several days after he was having a sore throat. Some days ago he had another one, the second this year. His brother has had a pinworm infection lately, and I suspect that R. is having a latent infection of pinworms and the fit is a reaction to it. I read on pubmed.com that irritability, even post traumatic disorder like symptoms can show up in children who have a pinworm infection. My questions are: Is it possible that these fits are some kind of inflammation going on somewhere in his brain and what can I do at that moment to calm him? I don't want to give him psychiatric drugs. Could have vaccines contributed to it? Vaccines can cause ASIA syndrome (Autoimmune/inflammatory syndrome induced by adjuvants). I feel very guilty that I continued to vaccinate him although he was having this neurological problem (which now is a psychiatric problem). I did space out the vaccines. Has any of you experience in using alternative methods for calming an aggressive explosion? I read in the comments in the forum that protein bars are good (I have added it to the list). I am thinking of giving him vitamin C. He is addicted to sugar, and probably uses it to calm himself, but in the long run I am afraid it just makes it worse. Sugar is considered a kind of drug by some psychologists. I would appreciate any suggestions.