Strattera has been on the market since the end of 2002. When if first came out, it listed mood swings as an adverse side effect. I was in touch with a woman whose son was in the clinical test for the approval of the drug. Her son had to drop out of the study at 13 weeks, IIRC, because of what they called mania. She described anger, aggression, hostility. There was nothing in the final report or the first version of the prescribing information to indicate any child in the study had issues like that. Then the whole antidrpessant thing hit the fan and Strattera is required to have the same black box warning/other warnings as any of the other antidepressants.